Diabetes and Obesity

3rd Dec

Being overweight places extra stress on your body in a variety of ways, including your body’s ability to maintain proper blood glucose levels. In fact, being overweight can cause your body to become resistant to insulin. If you already have diabetes, this means you will need to take even more insulin to get sugar into your cells. And if you don’t have diabetes, the prolonged effects of the insulin resistance can eventually cause you to develop the disease. For more details, contact us at http://bit.ly/1SnAE8I
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Fitness Tips for Senior Citizens

Fitness Tips

As you grow older, an active lifestyle is more important than ever. Regular exercise can help boost energy, maintain your independence, and manage symptoms of illness or pain. Exercise can even reverse some of the symptoms of aging. For more details, contact us at http://bit.ly/1SnAE8I #WeightLoss #Obesity #Bariatrics #FitnessTips

The Da Vinci Surgical System


The da Vinci Surgical System, a four-armed robotic medical device, is quickly becoming one of the most valuable assistants in the operating room. At a time when weight loss surgery assists patients with weight loss, the da Vinci Surgical System is offering them improved surgical outcomes and a quicker recovery with less pain.
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Genetics linked to Obesity


Researchers at Imperial College London led by Dr Tony Goldstone, a Consultant Endocrinologist at Imperial College of London, UK, found that two gene variants – FTO and DRD2 – influenced activity in the brain reward system when looking at pictures of high-calorie foods. The research suggests that part of the reason people with the FTO variant are more likely to have obesity may be because dopamine signals in their brain cause them to feel more reward and craving when presented with high-calorie foods.

Deep Brain Stimulation for Obesity


Deep brain stimulation (DBS) is widely accepted as an effective treatment for neurological conditions such as Parkinson’s disease, now researchers from the Ohio State University and University of Southern California, claim that the treatment could be used to treat obesity.


According to a review article in the journal Neurosurgery, Dr Alexander Taghva and colleagues claim recent understandings of the dysregulated reward circuitry of the brain may lead to developing in tackling obesity.


Drug treatments for obesity have targeted the homeostatic (self-regulating) mechanism regulating appetite and body weight. The homeostatic mechanism is thought to involve the feeding centre in the hypothalamus, which produces hormones (such as leptin and insulin) that affect feeding behaviour.


Initial experiments exploring DBS as a treatment for obesity have targeted the hypothalamus. However, as with drug options focusing on the homeostatic mechanisms, success has been limited


More recent studies have explored a different mechanism. Specifically, the dysregulated reward circuitry, of the brain. Research has suggested that obesity is associated with a relative imbalance of the reward circuitry and shows that obese subjects are more impulsive and less able to delay gratification. The reward circuitry is intimately interconnected with the homeostatic mechanisms.


The researchers have suggested that DBS could be used to deliver a mild electrical current to stimulate that area of the brain, with the goal of interrupting the feeding behaviour in obese patients.


They outline evidence implicating several different brain areas involved in the brain’s reward circuitry, particularly the frontostriatal circuitry, which could be useful targets for DBS.


Previous reports in individual patients have suggested that DBS performed for other reasons, particularly severe obsessive-compulsive disorder, have unexpectedly had unpredicted beneficial effects on addictive behaviours like smoking and overeating.


Taghva and colleagues hope their review will open the way to further exploration of DBS, perhaps in combination with therapies targeting the homeostatic mechanism.

Source: Bariatricnews.net